Grile Farmacologie

1. Anti HTA +:( pica 100% cel putin 3 subiecte din urmatoarele:)

-IR:

1. Diur Tiazidice

2. Ansa-Furos

3. Spirono-K

4. BB cu elim renala

5. Ca Bloc

6. IEC

-DZ:

1. IEC,

2. Ca Bloc

3. Beta1B

4. La varst Diur Tiazidice

5. La varst Diur Aldost

-Dislipid:

1. IEC

2. Ca Bloc

-BIP:

1.IEC,

2.Ca Bloc,

3.-1B

-BIC:

1.Ca Bloc cu eff prelungite Nu prima gener,

2. BB,

3. Nitrati,

4. IEC inclusiv prev sec

-Sarcina:

1. -Metil Dopa,

2. Labetalol,

3. Prazosin,

4. MgSO4,

5. BB=Ateno-Metoprolol,

6. Ca Bloc=Nifedipina Verapramil

-IC:

1. IEC-mortalitatea cu 1/6,

2. B1B-selective-Metoprol,Carvedilol Mortalitata cu ¼

-AVC: by yury

-Prev I:

1. IEC

2. Ca Bloc

3. Diuretice

4. Alfa1Bloc

-Prev II:

1. IEC,

2. -1Bloc/

Labetolol iv. urgenta, Nitroprus Na-Creste p i.cran

-HVS:

1. IEC

2. BAT2

3. 1B

4. Clonidina

5. -Metildopa

6. -Bloc

2. Ce NU se da in HTA + Sarcina:1.IEC-tulb crest=IRen fat,

2.BRAT2,

3.Diuretice-Vol Plasm,Circ Placenta,Nutrit Fat

3. Diuretic in HTA: Tiazid: ICC, HTA-1. varstnic 2. sistolica izolata varstnic 3. de o: apicana

Ansa: ICC, Insuf.Renala

Aldost: ICC, Post IMA

4. Asociere de

-Diuretice

-AntiHTA 1. Diuretic + BB Principiul: Sinergism-efecte pozitive prin 2 mecanisme diferite

2. Diuretic + IEC Antagonism-eff adv

3. Ca Bloc din tulb de ritm + BB protecrot fata de tulb de ritm

4. Ca Bloc + IEC – eficienta in scaderea TA

5. BB + -B – rar

-AA: 1. IA(Clonidina, Procainamida)+IB(Mexiletina)Can Na Activ vs Can Na Inact Interz: 1.Nu se Asc ac Cls/SubCls:IA+IC

2. I+BB(no Sotalol) 2. Dc QT NU – IA, Amiod, Sotalol

alte : 1.Propranolol+Metixilina/Flecainida - Diminua Efectul Proaritmic 3. Amiod+BB – eff Aditive

2.IA+Sotalol - Date clinice incomplete

3.Clonidina+Verapamil – Hipotensiune

4.Disopiramida+Verapamil

5. Propafenona+Chinidina/Procainamida

5. Indicatii :Aritmie+HTA:1.BB selective, 2.Ca Bloc Verap.Dilti (DupaK posttrat diur–favor EctopiiV Proaritmigene

6. Eff Adv: CI – AA:

-AA 1. Amiodarom: Fibr Pu, Neuropat Perif, Depoz Cornee, Disf Hep+Tir, B.Pu, Hep, Neuropat

2. BB: BeSpasm, HiperGlic Asm, D-InsDep

3. CaBloc: Icc, BAV Disf V, Tulb Cond

4. Disopiarmida: ICC, Torsada Vf, Ret Urin, Glauc, Creste QT, Tulb Ritm QT>, Prostatism, Glaucom, IR

5. Flecainida: Creste Mortalitatea Post IM, BradiAritm Tulb Cond,

6. Procainamida: Sdr.Lupoid, Agranulocitoza Artrita Cr, Discrazie Sg

7. Lidocaina+Mexilitina: Tremor Parkinson

8. Propafenona: ICC, BrSpasm, ProArtim Asm, Tulb Cond, Disf VS

9. Chinidina: Torsada Vf, Creste QT, Diaree, HipoK B.Dg Cr, Qt>, HipoK

10. Sotalol: Torsada Vf, BrSpasm, DZInsDep Asm, DZ InsDep, QT>, HipoK

-Brdilat 2Adr:Toleranta,Agitatie, Tremor, Nervoz, Cefalee, Transpir, Slabici, Roseata Pielii, Greata, Voma Aritmii HTA, HipoK+

-CoSt:Sistemic-1.Metab-Intol Gluc, Obez, Dislip, Proteoliz; 2.Os:AbsCA, NecrAvsc Cap Femur, Osteopor; 3.CV:Retent.Hd, HTA, ATS; 4.Supresia Sys Imm-Vulnerab La Inf; 5.M.Striata;Miopatie, Mas Musc, 6.Piele-Atrofie, 7.HipoGonadism8.Ulcer Peptic, 9.Cataracta, 10.Neuro:Euforie, Depresie, Tulb Somn, Ideatie Psihotica, 11.Tulbcopii:secr horm de, Inhib Ef Fact de Insulin Like, Local: Disfonie-Fav dezv Fungi Candid OroFar, Iritatia, Gat Tuse

-Stabil Mast: Cefalee, Gat uscat, Iritatie, BrSpasm tranzitoriu, Tuse, Roseata Tegumentara

-Sulfasalazina:Cefa Fe Greata Diaree DiscGastric, Anemie Megalobabs Ac.Fol, R.Alerg:Artralgii, Hemoliza, Agrnul, Tt-penie,

-ImmSupr:DerivTioguanina-Suprima MadHePoet, 2.Mtxat-SupresMed, Alopecie, Nefrotox, EpitIntest, 3.Inflix-InfRespSupIgASecrt

-IPP: Omeprazol-HiperGastrienemie Secundara, HiperPlazia Mucoasei Gastrice

-Teofilina C-V: TahicSinusala, TSV, ESV, FiA, Ftt, TahicAtriala, TahicMultifocala, Aritmie cu instabilitate hemodinamica

6. AA Neclasificate:1.Atropina -Bradic Sinusala, 2.Adrenalina - Stop, 3.Izoprenalina-Bloc, 4.Dogoxin - FiA, . . 5.Adenozin-TSV, 6.CaCl2 - TV PrinHiperK, 7.MgCl2 - FiV, Intoxi Digitala, Torsada Vf

7. Efecte CoSt: Confirmat:Inh Local:Nev De Cssyst, simpt sau Exacerb AB,Nev DeBrDiladr de urgenta,

Crize Noct /Echivalent AB Noct -Tuse, Imbunatat Indici Calitate Vietii, Ameli Fct Pu,

Posibil:Cz Deces, Vit Declin Fct Pu, Per De Remisie Sustinuta a Crizelor

8. Efecte BrhDil:BrDil, StabMast, Inhib Eliber LT, PermeabVasc, Exudat+EdemCA, Clearance MucoCil, Secr Mucus

9. Sv BB in IC: Risk De aritmii- Eff Anti Aritmic, Prin Activ Simpatice In ICC

10. Clase de Medicamente in IC: IEC, BB, Ca Bloc, Nitriti, Diuretice

11. Medicamente ce actioneaza pe Alfa 2 Centrali: Clonidina

12. Cond Pat HTA+BB: Angina P, Post IMA, ICC, Sarcina, Tahiaritmii, Cele cu Act Intrinseca- Sunt Tahicardizante=CI

13. NU se daHTA+BB: Obligatorii-Astm, BPOC, BAV 2/3, Posibile:BoalaVascPerif, Intoler la Gluc, Pers Fiz Active - Atleti

14. Cond Pat Ce Det Aritmii:TS: Durere, HipoVol, IC, Tireotox, Anxietate

15. In ce aritmii se da Digoxina: Fi A: 62,5-250 g/zi p.o. corelata cu varsta

16. TorsadaVarfuri: MgCl2-2g in 1-2 min, repetat la 5-10 min, Alternativ Isoproterenol sau Pacing ( QT )

17. Genza Torsada: Bloc K+, Antihist, Fenotiazide, AntiDepres3Ciclice, Ketoconazol, Dieta proteica Lichida

18. AAQT: Quinidina Disopiramida Amiodarona Sotalol Bepidil Probucol Prenilamida Der.Triciclici Fenitiazina Eritromicina Antihistaminice:Terfenadina Astemizol ; Creste QT pe fond de hipo K+Mg+

19. AAPRR--

20. AA Proaritmogene: IC,A, III-Sotalol

21. Cum actioneaza Clasa I pe PRefract

22. Cum actioneaza Clasa I pe PA:1a-, 1b-

23. Cum Actioneaza Clasa III: Durata Faza 3 PA PRE

24. Cum actioneaza Clasa IV pe Faza 0: Depolarizarea Spontana; Frecventa Conducere AV; PA

25. In ce afectiuni se da Bloc-Adr:1. Hiper plazie Prostata, 2. Hiperlipidemie

26. Clase Laxative:1.Volum-MetilCeluloza,Plicarbophil,

2.Emoliente-Docusat Cu/Na,

3.Lubr-Ol.Parafina/Magnezia Usta,

4.Iritante-Senna,fftaleina,Ol.castor,Ol.Ricin

5.Osmotice-MgSO4. Citrat. PolietilenGliolElectroliti = Fortrans, Lactuloza -scade NH3 Encef. portala,

27. Indicatii MgSO4:= laxative osmotice in constipatie, Atrag apa =  Bol Fecal

28. UG+HPClase: 1. Antisecr-IPP:Omepraz40, Lansopraz15-30, Pantopraz40,

2. BRH2:Cimet800Zi*No,Ranit*300,Famot*40,

3. Protectoare Bi525x3/zi,

4. Abo:Metro400x3/zi, Tinidazol, Claritro500x2/zi, Amoxi500x3/zi

29. Boala Inf Int Clase

-1.5AminoSalicilati-Sulfasalozina,Mesalazina-Sulfapiridina4g.zi in 4 prize initial500mgx2/zi,Similar Olsalazina.

-2.GCz Prednison40mg/zi,

-3.ImmSupres:dc nu raspunde la 2•Deriv.de.Tioguamina=6MercaptoPurina 1.5mg/kg/zi, Azatiopurina2-2,5mg/kg/zi}3-6 luni•Metotrexat15-25mg/sapt im:Debut Ac Mai rapid de cat<<|Eff buna in B Crohn•Ciclosporina4mg/kg/zi infuzie c% sange tot 300-400mg/ml:Eff in RCUH ce nu rasp la 2

-4.Influximab Igce leaga TNF- pe carel neutralz

30. Eff Adv Cimetidina: Cefal,+/-Somn,Fatigab,Greata,Voma,Diaree,Constip,Tr-penie,Gin-mastie,Alopec,Impoten,Artralgie,Disc-Abd

31. IEC Indic: CI:

1. IC toate st, Sarcina

2. HTA-Cu risc Cresc+DZ, St.Bilat a.Renale

3. IMA, Post IM Cu disfunct VS, HIperK

4. Nefropatie Diabetica,

5. Protectie CV, Post IM Remodelare

32. Da Tahic Reflexa: clonidina,vdilat,directe,ieca

Aceste 2 pagini invatati la sfintenie, este scris exact ce trebuie completat la examen, Un sfat prietenesc de la cineva care a experimentat